There are 5 things that the Pineal gland is responsible for: Inner Eye xanonymous Being hairless left us vulnerable to fluctuations in weather since, in comparison to other primates, we must expend significant extra energy to produce body heat to stay warm. Keissler [in Russian],Mikrobiolohichny? Genres History. Other studies have demonstrated the potential application of the melanized fungi for the removal of radionuclides and heavy metals from aqueous solutions, providing an alternative means to affect cleanup of industrial effluent [16, 120, 160164]. 6 (December 2008): 525-31,https://doi.org/10.1016/j.mib.2008.09.013. on June 15, 2018, There are no reviews yet. Impressively, however, 90 percent of the mice that had been given melanin-richmushroomsor white mushrooms supplemented with melanin survived.29. It has been reported the use of melanin, a biopolymer with good biocompatibility and biodegradability, intrinsic photo-acoustic properties, binding ability to drugs, and chelating property to radioactive metal ions, as an efficient endogenous nanosystem for imaging-guided chemotherapy [152]. Large amounts of agro-industrial residues generated from diverse economic activities have attracted strong industry interest on the utilization of these residues as inexpensive substrates to support the growth of microorganisms in bioprocesses. 26. Genres History. Despite its high biocompatibility, the use of melanin as a novel biomaterial in pharmaceutical and biomedical applications reported in literature is still scarce. 20. WebThe book features nearly all unknown secrets. Amazon.com: Melanin Research Foundation: Books 1 result RESULTS Melanin: Energy from Light and the Soul's Ascent by Melanin Research Foundation | May 3, 2015 20 Kindle $399$6.12 Available instantly Paperback $612 FREE delivery Sat, Dec 10 on $25 of items shipped by Amazon Need help? There are 5 things that the Pineal gland is responsible for: Inner Eye This effect was observed for Cryptococcus neoformans, whose in vitro melanization has been associated with resistance against host effector cells, oxidants, microbicidal peptides, and amphotericin B [2325], and in Wangiella (Exophiala) dermatitidis, when the polyketide synthase gene WdPKS1 associated on melanin production was disrupted, this strain has become more susceptible to voriconazole and amphotericin B [26]. Melanins proposed ability to convert sunlight into metabolic energyakin to the way chlorophyll harvests sunlight in plantsmeans that our species should be reclassified from heterotrophic to photoheterotrophic, and, even more significantly, may raise the prospect that melanin offers protection against ionizing radiationwhiletransforming it into metabolically useful energy. Back To Tokyo Vittorio Brena LABEL: Yesenia GENRE: Deep House RELEASED: 2023-02-17 DOWNLOAD SIZE:: 17,32 MB TRACKS 1. Llaila O. Afrika. However, melanin has been observed to have other functions such as neuroprotection and energy production. 24. Melanin pigment of Fonsecaea pedrosoi has antioxidant potential by reducing Fe(III) to Fe(II), ensuring the balance of its redox chemical microenvironment and minimizing the effect of oxidation of fundamental structures on fungal growth [104]. Pseudomonas requires 3536C for its growth and pigment production, while in Monascus purpureus, maximum pigment production was observed at 30C with a reduction of the yield at 37C [48]. The Pineal gland is the first gland developed in your body, and appears in homo-sapiens a mere 3 weeks after conception. What advantages, then, could hairlessness impart? A study performed with melanin nanoparticles as biocompatible drug nanocarriers, using metronidazole (antibiotic drug), showed that melanin could be a very interesting nanocarrier drug release device because it strongly responds to pH, being a very interesting feature for the treatment of intestine and colon diseases, which would greatly benefit with pH targeting [142]. To investigate whether dietary melanin might confer some of these powers to animals, scientists at the Albert Einstein College of Medicine fed melanin-rich mushroomsthe kind most of usknow as Judass ear or jelly earto mice. Melanin has many other interesting properties, such as ultraviolet absorption, which has been utilized to prepare optical lenses or filters. Cracks in 100% nearly all topic of importance to you, like. In Monascus ruber, it was observed that the highest levels of pigments production were obtained at an aeration rate of 0.05 L min1, which appeared to be clearly sufficient for providing the fungus with oxygen and removing carbon dioxide [57]. Watch on QUALIFIED IMMUNITY PACKAGES POLICE STOP/ LAW & GOV FLASHCARDS (PSFC) & (LGFC) Rate this book. Packed with knowledge of the food of the gods. From the ink of the octopus to the protective colorings of bacteria and fungi, melanin offers protection against a variety of biochemical and predatory threats and chemical stressors, and, most famously, acts as a photoprotective factor againstultraviolet radiation. One partial explanation for its seeming supernatural capability is that the animals pecten, which is found enlarged in migrating birds who are subject to stressors such as hunger, thirst, hypoxia, and gravity, help the albatross contend with the elements by mediating the melanin-driven conversion of light to metabolic energy. 306 ratings 30 reviews. Cracks in 100% nearly all topic of importance to you, like. Addeddate 2018-06-15 13:47:24 Identifier MelaninWhatMakesBlackPeopleBlackByLlailaAfrikaPDF Identifier-ark ark:/13960/t6zw89t9z Ocr ABBYY FineReader 11.0 (Extended OCR) 50% Discount on the Remaining Status Law Classes NOT on Patreon! However, it is necessary to expand the knowledge about the structure-property-function relationships for the development of melanin-based technology. Owing to their ability to increase the permeability of the blood-brain barrier, the melanin is also useful as carriers for other therapeutic agents, which must reach brain tissue to produce their therapeutic responses [144]. This book, is designed to familiarize the Black Human with Melanin and its importance to life, memory processes, ancient African history, sunlight, music, dancing, anti-aging, anti-cancer, religion, electromagnetism, and any other scientific and cultural parameters. A piezoelectric sensor system capable of real-time detection of metal ions was constructed by cross-linking melanin onto the gold electrode of quartz crystal microbalance (QCM) and showed high sensitivity and selectivity to metal ions particularly for Hg(II) [138]. Cracks in 100% nearly all topic of importance to you, like. Human hairlessness occurred concurrently with an augmentation in the melanin content of the skin, paving the way for a process called photomelanometabolism.19In what is known as ultrafast internal conversion, melanin can convert 99.9 percent of potentially gene-damaging ultraviolet light into harmless heat, fulfilling both sun blocking and energy-generating functions.20. Other studies confirmed the indolic nature of the melanin produced by A. nidulans [11, 90]. The biosynthetic pathway of fungal dihydroxynaphthalene(DHN)-melanin. *Address all correspondence to: sponchia@iq.unesp.br. The A. auricula melanin displayed inhibitory activity on biofilm formation of the three bacterial strains, E. coli K-12, Pseudomonas aeruginosa PAO1, and P. fluorescens P-3, and there was a proportional reduction in biofilm biomass with the increase in pigment concentration. Fungal melanins are negatively charged, hydrophobic pigments of high molecular weight formed by oxidative polymerization from phenolic and/or indolic compounds, such as glutaminyl-3,4-dihydroxybenzene (GDHB) or catechol or 1,8-dihydroxynaphthalene (DHN) or 3,4-dihydroxyphenylalanine (DOPA). This result is related to melanin production during growth of the MEL1 mutant, since the biomass 48 hours is slightly pigmented, while the 72 hours biomass is dark due to the increased production of pigment [157]. The answer may be found in an article published in theJournalof Alternative and Complementary Medicine, in which Geoffrey Goodman and Dani Bercovich hypothesize that melanin may account for the reduction in body hair that occurred 2 million years ago, in an evolutionary trade-off that exchanged the endothermically protective coat of hair for the benefits conferred by melanin-mediated harvesting ofsunlight. Hermit93 2,799 views May 25, 2018 163 Dislike Share REEL NAGAS 28.5K subscribers Order Your Copy of the Great Book of Melanin Research Today!!! Capture a web page as it appears now for use as a trusted citation in the future. Amazon.com: Melanin Research Foundation: Books 1 result RESULTS Melanin: Energy from Light and the Soul's Ascent by Melanin Research Foundation | May 3, 2015 20 Kindle $399$6.12 Available instantly Paperback $612 FREE delivery Sat, Dec 10 on $25 of items shipped by Amazon Need help? You can download the paper by clicking the button above. Some studies suggest the possible use of melanin-coated nanoparticles in medicine, mainly for protecting patients against the harmful effects of gamma rays during radioimmunotherapy [34, 151]. These advances allow to elucidate the molecular mechanisms of the various biological functions of melanin [22]. According to the authors, these nanoshells have the potential use for environmental bioremediation, for example, to prevent the spread of radioactive contamination to ground water because the melanin is expected to encapsulate the radioactive particles and thereby reduce their spread. However, melanin has been observed to have other functions such as neuroprotection and energy production. In Agaricus bisporus, melanins are formed from DOPA by tyrosinase and from -glutaminyl-4-hydroxybenzene by peroxidase and phenolase [100]. 15. The study performed by [114] showed that the expression of inducible nitric oxide synthase gene decreased and lower levels of cytokines, such as IL-12 and TNF-, were observed when activated macrophages were incubated with melanized cells of the Fonsecaea monophora fungus. About the author. It was demonstrated that the melanin produced by fungus Lachnum singerianum YM296 significantly inhibited the formation of lipid peroxidation products and slowed down the aging process, elevating the levels of superoxide dismutase, glutathione peroxidase, and catalase and decreasing the level of malondialdehyde in mice liver and brain homogenate and serum, suggesting that this pigment could be used as a new anti-aging drug [109]. For example, the pigment production by Penicillium sp. neuromelanin. 1 (August 2011): 69-73,https://doi.org/10.1016/j.bioelechem.2011.04.009. This book, is designed to familiarize the Black Human with Melanin and its importance to life, memory processes, ancient African history, sunlight, music, dancing, anti-aging, anti-cancer, religion, electromagnetism, and any other scientific and cultural parameters. First published October 15, 2009. In addition, this pigment has a considerable interest biotechnological because it can be produced on a large scale with low cost, making its use for future practical applications economically advantageous. J101 reported that the yield of pigment at 25C was ten times higher than at 30C, probably due to long growing (120 hours) and lower viscosity of the broth at 25C compared to 30C [49]. 4.37. Ekaterina Revskaya et al., Compton Scattering by Internal Shields Basedon Melanin-Containing Mushrooms Provides Protection of GastrointestinalTract from Ionizing Radiation,Cancer Biotherapy and Radiopharmaceuticals27, no. Llaila O. Afrika. This pigment protects the conidia against digestion by proteases and hydrolases secreted by competitive microorganisms or against bactericidal and fungicidal proteins of animal origin, such as defensins, magainins, or protegrins [22]. 2 (April 1961): 440-41,https://doi.org/10.2307/1932103. Miroslav Blumenberg. WebThis volume goes over the brain hemispheres, history of religion, Black founders of civilization, the Sun, cosmology and cosmogony, the subjective and objective realms of being, analysis of cosmological system and view of man, spiritual anatomy of man, types of man and the cultivation of the spiritual man, the Tree of Life initiation system, Goodman and Bercovich, Melanin Directly Converts Light for VertebrateMetabolic Use, 190-202. In M. ruber, the use of glutamic acid as a nitrogen source showed promising results, either as stimulating the accumulation of extracellular pigments or contributing to increase the efficiency of the pigment production process [45]. Melanin, Radiation, and the Conversion of Light to Metabolic Energy. In our study with the hypermelanized mutant (MEL1) from A. nidulans, we observed an increase in the production of pigment when the initial pH of the culture was at 6.8 compared to pH 8.0 [50]. 103 pages, Paperback Published September 1, 2001 Vittorio Brena Back To Tokyo / Yesenia. Polymerization of exogenous substrates in this fungus occurs under the action of laccase [19]. At the same time you will be contributing to the Cop Stop Guardian Traffic Stop App! 103 pages, Paperback Published September 1, 2001 In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. Access to Any Private Q&A Livestream With Me! Uploaded by Studies have shown that the effect of melanin enhancing the survival of fungi under adverse conditions can be mainly due to its powerful free radical scavenger properties, acting as a sponge for other free radicals generated by the fungus in response to environmental stress [20, 29, 30]. These authors concluded that the cultivation in the total absence of light increased biomass and production of extracellular and intracellular pigments in all fungi. There are 5 things that the Pineal gland is responsible for: Inner Eye Feb 19, 2023. This will allow me to plunge deep into my bag of information acquired over the years as well as the knowledge gained from film school to create videos full time. By making research easy to access, and puts the academic needs of the researchers before the business interests of publishers. 27. 31. 22. Vittorio Brena Back To Tokyo / Yesenia. Scheme adapted from Ref. In experimental models, melanin can successfully shield bone marrow from such side effects. This Can Explain the Rapid Expansion of OurGenuss Brain,Medical Hypotheses84, no. Most significant, however, is the resulting necessity for the increased production of melanin, first as a sun protectant but secondarily as a means to endow humans with the ability to harness electromagnetic radiation for metabolic energy in a fashion similar to chlorophyll. Sorry, preview is currently unavailable. on the Internet. The chemical structure of melanin presents many oxygen-containing groups, including carboxyl, phenolic and alcoholic hydroxyl, carbonyl, and methoxy groups, which have the ability to bind to a broad spectrum of substances [153]. [34] reported that the extracellular melanin produced by the fungus S. commune was effective against human epidermoid larynx carcinoma cell line (HEP-2) in a concentration-dependent manner, indicating its potential application in cancer chemoprevention and chemotherapy. Although the molecular structure of fungal melanin remains enigmatic, significant progress has been made in understanding particular aspects of its macro- and microstructure. The metal chelation properties of melanin offer interesting possibilities for melanin-based metal ion sensing. In this study, we demonstrated that this melanin pigment did not induce gene mutations in different strains of Salmonella typhimurium used in the Ames assay. Gerald H. Pollack, Xavier Figueroa, and Qing Zhao, Molecules, Water, andRadiant Energy: New Clues for the Origin of Life,International Journal ofMolecular Sciences10, no. The evaluation of the effect of fungal melanin on non-tumor cells is also interesting because it may serve as alternative to acute in vivo toxicity testing, avoiding the indiscriminate use of animals. 1: the Great Oracle of Tehuti and the Egyptian System of Spiritual Cultivation by Ra Un Nefer Amen $33.33. Scientists have identified three forms of melanin in humans: eumelanin. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. Experimental evidence shows that the accumulation of 90Sr by conidia or mycelium by a range of microfungal species is greater in pigmented than in unpigmented species [158]. isolated from a wall surface, suggesting the application of these nanoparticles as effective paint additives. Visit the help section or contact us Eligible for Free Shipping Goodman and Bercovich, Melanin Directly Converts Light for VertebrateMetabolic Use, 190-202. $33.33. Mice treated with melanin-coated nanoparticles have higher white blood cell and platelet counts than control mice after radiation treatment [117]. With the current knowledge about physical and chemical properties and the broad spectrum of biological activities, fungal melanins have attracted growing interest for their potential use in the fields of biomedicine, dermocosmetics, nanotechnology, and materials science. In general, glucose, an excellent carbon source for growth, interferes with the formation of many secondary metabolites, including pigments. WebMelanin: The Chemical Keys to Black Greatness (Vol. (PDF) melanin melanin Authors: Dr Sumanta Mondal GITAM (Deemed to be University) Abstract Melanin is a natural skin pigment. The precursor of melanin in Agaricus bisporus and other Basidiomycetes is a metabolite of the shikimic acid pathway--glutaminyl-4-hydroxybenzene oxidized under the action of peroxidase and/or phenolase into -glutaminyl-3,4-benzoquinone, followed by its polymerization [80]. However, M. purpureus was not able to grow in media containing peptone, and a maximum yield of the pigment was achieved when the media were supplemented with yeast extract (1%) and monosodium glutamate (5%) as nitrogen source [41]. @DESIRE | You #Enslave or are-Enslaved. Melanin is a substance in the skin that produces skin pigmentation. 100% Health cracked, 100% Universal Laws (operating here cracked, how to take advantage), In 100% describes Biblical Law of Jesus Christ which operates in this reality and leads web pages 23. This turning pointfirst the hairlessness, then the expansion of the brainmay be directly traced back to melanin, exemplifying how paramount it is to our species resilience and survival. Among the physical properties of melanin, the electrical conductivity is one of the most interesting to investigate in the perspective of technological application. 306 ratings 30 reviews. Capture a web page as it appears now for use as a trusted citation in the future. These results can be explained by melanin or other natural pigments present in the cell wall of these fungi that can act as the radiation receptor and/or as an energy transporter for metabolism. 68 pages, Paperback. Melanin is a substance in the skin that produces skin pigmentation. Synthetic melanin thin films deposited by spray-coating presented features ascribed to an amorphous semiconducting material [134]. Buy on Amazon. It has also been reported that melanin thin films possess highly desirable physical and biological properties that make them ideal for organic bioelectronic devices [130]. Melanin possesses physicochemical properties and biological activities that make it a suitable biomaterial for a wide range of applications in cosmetic, pharmaceutical, electronic, and food processing industries. WebThe book features nearly all unknown secrets. This hypothesis is supported by the discovery of melanized fungi in soils contaminated by radioactive nuclides and areas around the damaged Chernobyl nuclear reactors, which not only survive high radiation levels but also have enhanced growth upon exposure [16, 19, 119, 120]. Print length 103 pages Language English Publisher Lushena Books Publication date Recent studies have demonstrated that, in addition to the ability of transferring electrons arising under the action of radiation, melanin also possesses ionic conductivity due to its ability to transform any type of radiation energy not only into heat but also use it for the maintenance of redox processes in cells [118]. Studies have shown that it is possible to use melanin as an ultraviolet, visible and near-infrared absorbing pigment in opthalmic devices, protective eyewear, windows, packaging material, umbrellas, canopies, and other similar media suitable for providing protection from radiation [139, 140]. pheomelanin. WebFor those important aspects of pigment cell research that do not fall entirely within the scope of the study, such as human cutaneous melanoma or non-cutaneous melanogenesis, and for a more detailed discussion of melanins, melanogenesis, and their applications, the readers are referred to a number of reviews (e.g. In a similar study, [56] noted that the production of pigment by Monascus species also was favored when the fungus was grown in the dark. Silver nanostructures synthesized with melanin derived from Y. lipolytica displayed excellent antifungal activity against an Aspergillus sp. Thin films deposited by spray-coating presented features ascribed to an amorphous semiconducting material 134! Of melanin offer interesting possibilities for melanin-based metal ion sensing has been made in particular. Structure-Property-Function relationships for the development of melanin-based technology business interests of publishers Feb 19, 2023 reviews.. 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